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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
13.5 DPC

11 matching records from 11 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Afdn  afadin, adherens junction formation factor   (Synonyms: 5033403D15Rik, AF6, Afadin, I-afadin, Mllt4, S-afadin)
Results  Reference
1J:271772 Dewitz C, Pimpinella S, Hackel P, Akalin A, Jessell TM, Zampieri N, Nuclear Organization in the Spinal Cord Depends on Motor Neuron Lamination Orchestrated by Catenin and Afadin Function. Cell Rep. 2018 Feb 13;22(7):1681-1694
1J:215584 Gil-Sanz C, Landeira B, Ramos C, Costa MR, Muller U, Proliferative defects and formation of a double cortex in mice lacking Mltt4 and Cdh2 in the dorsal telencephalon. J Neurosci. 2014 Aug 6;34(32):10475-87
1*J:61349 Kanai-Azuma M, Mattick JS, Kaibuchi K, Wood SA, Co-localization of FAM and AF-6, the mammalian homologues of Drosophila faf and canoe, in mouse eye development. Mech Dev. 2000 Mar 1;91(1-2):383-6
1J:102364 Koike C, Nishida A, Akimoto K, Nakaya MA, Noda T, Ohno S, Furukawa T, Function of atypical protein kinase Clambda in differentiating photoreceptors is required for proper lamination of mouse retina. J Neurosci. 2005 Nov 2;25(44):10290-8
1*J:180113 Lachke SA, Higgins AW, Inagaki M, Saadi I, Xi Q, Long M, Quade BJ, Talkowski ME, Gusella JF, Fujimoto A, Robinson ML, Yang Y, Duong QT, Shapira I, Motro B, Miyoshi J, Takai Y, Morton CC, Maas RL, The cell adhesion gene PVRL3 is associated with congenital ocular defects. Hum Genet. 2012 Feb;131(2):235-50
1J:240358 Maeta K, Edamatsu H, Nishihara K, Ikutomo J, Bilasy SE, Kataoka T, Crucial Role of Rapgef2 and Rapgef6, a Family of Guanine Nucleotide Exchange Factors for Rap1 Small GTPase, in Formation of Apical Surface Adherens Junctions and Neural Progenitor Development in the Mouse Cerebral Cortex. eNeuro. 2016 May-Jun;3(3):ENEURO.0142-16.2016
1*J:78857 Manabe N, Hirai S, Imai F, Nakanishi H, Takai Y, Ohno S, Association of ASIP/mPAR-3 with adherens junctions of mouse neuroepithelial cells. Dev Dyn. 2002 Sep;225(1):61-9
1J:90052 Okabe N, Ozaki-Kuroda K, Nakanishi H, Shimizu K, Takai Y, Expression patterns of nectins and afadin during epithelial remodeling in the mouse embryo. Dev Dyn. 2004 May;230(1):174-86
1J:304680 Skarlatou S, Herent C, Toscano E, Mendes CS, Bouvier J, Zampieri N, Afadin Signaling at the Spinal Neuroepithelium Regulates Central Canal Formation and Gait Selection. Cell Rep. 2020 Jun 9;31(10):107741
1*J:82002 Takekuni K, Ikeda W, Fujito T, Morimoto K, Takeuchi M, Monden M, Takai Y, Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouse. J Biol Chem. 2003 Feb 21;278(8):5497-500
1J:209314 Yamamoto H, Maruo T, Majima T, Ishizaki H, Tanaka-Okamoto M, Miyoshi J, Mandai K, Takai Y, Genetic deletion of afadin causes hydrocephalus by destruction of adherens junctions in radial glial and ependymal cells in the midbrain. PLoS One. 2013;8(11):e80356

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory